Tuesday, August 9, 2022

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Shared Instrumentation Grant (SIG) Program (S10)

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    93.351, 93.859

    Funder Type

    Federal Government

    IT Classification

    B - Readily funds technology as part of an award


    National Institutes of Health (NIH)


    The purpose of this funding opportunity is to continue the Shared Instrumentation Grant (SIG) Program administered by ORIP. The objective of the Program is to make available to institutions expensive research instruments that can only be justified on a shared-use basis and that are needed for NIH-supported projects in basic, translational or clinical areas of biomedical/behavioral research. The SIG Program provides funds to purchase or upgrade a single item of expensive, specialized, commercially available instrument or an integrated instrumentation system. An integrated instrumentation system is one in which the components, when used in conjunction with one another, perform a function that no single component could provide. The components must be dedicated to the system and not used independently.

    Types of supported instruments include, but are not limited to: X-ray diffractometers, mass and nuclear magnetic resonance (NMR) spectrometers, DNA and protein sequencers, biosensors, electron and light microscopes, cell sorters, and biomedical imagers. Applications for "stand alone" computer systems (supercomputers, computer clusters and data storage systems) will only be considered if the instrument is solely dedicated to biomedical research.

    All instruments, integrated systems, and computer systems must be dedicated to research only.

    Each applicant institution must propose a Program Director/Principal Investigator (PD/PI) who can assume administrative and scientific oversight responsibility for the requested instrumentation.

    The PD/PI also will be responsible for:

    • Requesting no-cost extensions of the project period, if needed;
    • At the end of the project period, preparing (and working with the institution to submit) a Final Progress Report (FPR) that describes the purchased instrument, lists all users and publications resulting from use of the instrument, and outlines the value of the instrument to the investigators and to the institution as a whole.
    • Submitting Annual Usage Reports (AURs) of the instrument to the NIH for a period of four years after the project end date.

    An Advisory Committee must be named to assist the PD/PI in administering the grant and overseeing the usage of the instrument.

    The PD/PI and the Advisory Committee are responsible for the development of guidelines for:

    • Maximum utilization of the instrument, including time allocation;
    • A detailed plan for the day-to-day management and safe operation of the instrument;
    • A plan to ensure that access to the instrument is limited to users whose projects have received approval from institutional human subjects, animal welfare or biosafety committees, as applicable;
    • A financial plan for the long-term operation and maintenance of the instrument during the post-award period;
    • The relocation of the instrument within or outside the institution or changes of ownership, if such changes are necessary;
    • Recommending a new PD/PI, if such a need arises.

    History of Funding

    Approximately $35,000,000 was awarded in total funding for FY20 for 75 awards.

    Additional Information

    The SIG Program will not support requests for:

    • An instrument with a base cost of less than $50,000;
    • Multiple instruments bundled together;
    • Purely instructional equipment;
    • Instruments used for clinical (billable) care;
    • Institutional administrative management systems, clinical management systems;
    • Software, unless it is integral to the operation of the requested equipment;
    • General purpose equipment or an assortment of instruments to furnish a research facility and equipment for routine sustaining infrastructure (such as standard machine shop equipment, standard computer networks, autoclaves, hoods, and equipment to upgrade animal facilities).
    • Disposable devices, office furniture, and supplies;
    • Alteration or renovation of space to house the instruments.

    Not Allowed: Only accepting applications that do not propose clinical trials.


    Guanghu (Jeff) Wang

    Guanghu (Jeff) Wang
    Office of Research Infrastructure Programs (ORIP)
    9000 Rockville Pike
    Bethesda, MD 20892

    Christina Liu

    Christina Liu
    National Institute Of General Medical Sciences (NIGMS)
    9000 Rockville Pike
    Bethesda, MD 20892
    (301) 496-4000

    Karen Brummett

    Karen Brummett
    Office of Research Infrastructure Programs (ORIP)
    9000 Rockville Pike
    Bethesda, MD 20892

  • Eligibility Details

    Eligible applicants include:

    • Higher Education Institutions
    • Public/State Controlled Institutions of Higher Education
    • Private Institutions of Higher Education

    The following types of Higher Education Institutions are always encouraged to apply for NIH support as Public or Private Institutions of Higher Education:

    • Hispanic-serving Institutions
    • Historically Black Colleges and Universities (HBCUs)
    • Tribally Controlled Colleges and Universities (TCCUs)
    • Alaska Native and Native Hawaiian Serving Institutions
    • Asian American Native American Pacific Islander Serving Institutions (AANAPISIs)

    Nonprofits Other Than Institutions of Higher Education

    • Nonprofits with 501(c)(3) IRS Status (Other than Institutions of Higher Education)
    • Nonprofits without 501(c)(3) IRS Status (Other than Institutions of Higher Education)

    Deadline Details

    Applications are due June 1, 2023. A similar deadline is anticipated annually.

    Award Details

    Approximately $35,000,000 is anticipated to be available in total funding for FY2023 to fund up to 75 awards. Applications will be accepted that request a single, commercially available instrument or integrated system which costs at least $50,000. The maximum award is $600,000. Awards will last for only 1 year. Cost sharing/matching is not required.

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